产品名称 Seriniquinone from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H14840
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameSeriniquinone
DescriptionPurity >98% by NMR, TLC. Seriniquinone is a new natural product isolated from a marine bacterium of the genus Serinicoccus. Displays selective toxicity against a distinct set of cell lines (within the NCI 60 panel) predominantly melanoma. Upon cellular treatment, seriniquinone was found to localize in the endoplasmic reticulum. Within 3 hours cells underwent autophagy followed by death via a caspase-9 apoptotic pathway. The target of seriniquinone was identified as the small protein, dermcidin as determined using an immunoaffinity approach.
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Other NamesDinaphthol[2,3-b:2',3'-d]thiophene-5,7,12,13-tetraone
Gene, Accession, CAS #CAS: 22200-69-7
Catalog #LS-H14840
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Order / More InfoSeriniquinone from LIFESPAN BIOSCIENCES INC.
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