| 产品详情 |
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| Antigenic Specificity | SPN / CD43 |
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| Clone | rSPN/839 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A/G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SPN / CD43 Antibody (clone rSPN/839) LS-C751368. Specificity: It recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb rSPN/839, called b as opposed to a for rSPN/839. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. |
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| Immunogen | Recombinant full-length human CD43 protein. Antigen Molecular Weight: 95, 115, or 135 kDa |
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| Other Names | SPN, GPL115, Leukosialin, Leukocyte sialoglycoprotein, Galactoglycoprotein, GALGP, Sialophorin, LSN, CD43, CD43 antigen |
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| Gene, Accession # | SPN, Gene ID: 6693 |
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| Catalog # | LS-C751368 |
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| Price | |
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| Order / More Info | SPN / CD43 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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