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| Antigenic Specificity | SPTA1 / Alpha Spectrin, aa356-475 |
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| Clone | rSPTA1/1833 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A/G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SPTA1 / Alpha Spectrin Antibody (aa356-475, clone rSPTA1/1833) LS-C751371. Specificity: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. |
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| Immunogen | Recombinant fragment of human SPTA (around aa356-475). Antigen Molecular Weight: 240 kDa |
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| Other Names | SPTA1, EL2, Erythroid alpha-spectrin, HS3, Alpha-I spectrin, HPP, SPH3, SPTA |
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| Gene, Accession # | SPTA1, Gene ID: 6708 |
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| Catalog # | LS-C751371 |
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| Price | |
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| Order / More Info | SPTA1 / Alpha Spectrin, aa356-475 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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