| 产品详情 |
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| Antigenic Specificity | CD275 / B7-H2 / ICOS Ligand |
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| Clone | MIH11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:1 - 1:5), IHC, IHC-Fr |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD275 / B7-H2 / ICOS Ligand Antibody (clone MIH11, FITC) LS-C58043. Detects CD275, also known as ICOS ligand (inducible T cell co-stimulator ligand). CD275 is a member of the B7 family, and interaction with its receptor CD278 (ICOS) plays an important role in T cell co-stimulation and inflammatory immune reactions. CD275 is expressed on activated B-cells, monocytes and dendritic cells and is also induced on non-lymphoid tissue cells such as endothelial cells, epithelial cells and muscle cells. CD275 has an important physiological role in the reactivation of effector/memory T cells on the endothelium, thus controlling entry of immune cells into inflamed tissue. The CD278-CD275 pathway is thought to be critical in the immune response to transplants, allergies and autoimmune diseases. Reported to partially block the interaction between CD275 and CD278. |
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| Immunogen | CD275 - L cells. |
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| Other Names | ICOSLG, B7RP1, B7 homolog 2, B7 homologue 2, B7-H2, B7H2, B7RP-1, CD275 antigen, ICOS ligand, GL50, ICOS-L, ICOSL, KIAA0653, B7-like protein Gl50, B7-related protein 1, CD275, LICOS |
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| Gene, Accession # | ICOSLG, Gene ID: 23308 |
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| Catalog # | LS-C58043 |
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| Price | |
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| Order / More Info | CD275 / B7-H2 / ICOS Ligand Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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