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| Product Name | Actin Polymerization/Depolymerization Assay Kit (Fluor) |
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| Description | Actin, a highly conserved and abundant protein in eukaryotic cells, is one of the major components of cytoskeleton. It can be found as monomeric globular protein, called G actin or it can polymerize into filamentous actin, named F actin. Actin plays major roles in cell division, cell motility, cell signaling, organelle movement, etc. Mammals have 6 isoforms of Actin, which can be divided into 3 classes, a, Beta and ?. Muscle Actin is a class and all other non-muscle actins belong to Beta and ? classes. Understanding the effect of different drugs, proteins, etc. on Actin Polymerization and Depolymerization is very important for understanding cellular machinery, more importantly because Cytoskeleton is a very important target for cancer therapy. The Actin Polymerization/Depolymerization Assay Kit can be used to study the effect of different compounds, proteins and tissue extracts on Actin polymerization and depolymerization. The kit utilizes a proprietary Pyrene-labeled Actin molecule that develops a higher fluorescent signal if it undergoes polymerization. The signal can be easily detected using a fluorescence microplate reader. The assay is simple, high- throughput compatible, and can be completed in less than three hours. Sample types: chemotherapeutic agents, protein, tissue extracts |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Study and quantitate the effect of different compounds, proteins and tissue extracts on Actin polymerization and/or depolymerization. Evaluation of critical concentrations of actin polymerization in different conditions |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-K497 |
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| Order / More Info | Actin Polymerization/Depolymerization Assay Kit (Fluor) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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