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| Product Name | PD 153035 (hydrochloride) |
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| Description | Purity >98%. Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR) has been associated with cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. PD 153035 is a highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM; IC50 = 29 pM). It has been shown to rapidly suppress autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells, as well as to selectively block EGF-mediated cellular processes, including mitogenesis and early gene expression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-bromophenyl)-6,7-dimethoxy-4-quinazolinamine, monohydrochloride, AG-1517 |
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| Gene, Accession, CAS # | CAS: 183322-45-4 |
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| Catalog # | LS-H9294 |
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| Price | |
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| Order / More Info | PD 153035 (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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