| 产品详情 |
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| Product Name | Exendin-4 (acetate) |
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| Description | Purity >98%. Exendin-4 is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor (Ki = 136 pM). By activating the GLP-1 receptor, it stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma BetaTC-1 cells, supporting efficacy in type 2 diabetes. Exendin-4 was first isolated from the venom of H. horridum and consequently synthesized, with the recombinant peptide referred to as 'exenatide.' Exenatide protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neuropathies associated with type 2 diabetes and in neurodegenerative diseases. Exenatide also has anxiolytic and anti-depressant effects and induces satiety. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Exenatide Acetate |
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| Gene, Accession, CAS # | CAS: 914454-01-6 |
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| Catalog # | LS-H7747 |
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| Order / More Info | Exendin-4 (acetate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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