| 产品详情 |
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| Product Name | STF-31 |
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| Description | Purity >98%. Glucose transporter 1 (Glut1) is an inducible carrier of pentoses and hexoses, including glucose. STF-31 is an inhibitor of Glut1 (IC50 = ~1 µM) that blocks glucose uptake. It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress Glut1. Although STF-31 binds Glut1, suggesting a direct effect, STF-31 also inhibits nicotinamide phosphoribosyltransferase, an enzyme that induces Glut1 expression. STF-31 is also toxic to human pluripotent stem cells (hPSCs) and can be used to selectively eliminate hPSCs from mixed cultures. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide |
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| Gene, Accession, CAS # | CAS: 724741-75-7 |
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| Catalog # | LS-H10042 |
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| Order / More Info | STF-31 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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