| 产品详情 |
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| Product Name | SRPIN340 |
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| Description | Purity >98% (NMR, HPLC). SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 uM).1 Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Inhibits viral replication by inhibition of host SR protein kinases. SRPIN340 modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy and controls VEGF-mediated tumor angiogenesis in xenografts. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide |
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| Gene, Accession, CAS # | CAS: 218156-96-8 |
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| Catalog # | LS-H14858 |
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| Order / More Info | SRPIN340 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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