| 产品详情 |
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| Product Name | WWL123 |
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| Description | Purity >95%. The serine hydrolase known as Alpha/Beta-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol to regulate its availability at cannabinoid receptors. WWL123 is a brain-penetrant inhibitor of ABHD6 (IC50 = 0.43 µM) that demonstrates >10-fold selectivity for ABHD6 compared to a panel of ~35 other serine hydrolases. Inhibition of ABHD6 by WWL123 has been used to decrease seizure incidence in a genetic mouse model of juvenile Huntington's disease as well as in chemically-induced epilepsy models. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-([1,1'-biphenyl]-3-ylmethyl)-N-methyl-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester |
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| Gene, Accession, CAS # | CAS: 1338575-41-9 |
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| Catalog # | LS-H10505 |
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| Order / More Info | WWL123 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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