| 产品详情 |
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| Product Name | WY-14643 |
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| Description | Purity >98% (NMR, HPLC). WY-14643 is a selective PPARa agonist (EC50=0.63, 32 and >100 uM for PPARa,g and d, respectively). Displays anti-inflammatory activity and reduces LPS-induced inflammation in alveolar epithelial cells. Induces ``browning'' of white adipocytes in combined treatment with retinoic acid. Stimulates ADAM10-mediated proteolysis of amyloid precursor protein in a mouse model. Down regulates NFkB transcriptional activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid |
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| Gene, Accession, CAS # | CAS: 50892-23-4 |
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| Catalog # | LS-H14501 |
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| Order / More Info | WY-14643 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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