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| Product Name | XCT790 |
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| Description | Purity >97%. XCT790 is an inverse agonist of estrogen-related receptor alpha (ERR alpha ; IC50 = ~300-500 nM). It demonstrates 90-100% inhibition of ERR alpha constitutive activity and has no significant activity at related nuclear receptors at 10 µM. XCT790 associates with the ligand-binding domain of ERR alpha and blocks ERR alpha /PGC-1 alpha -dependent signaling, suppressing the expression of monoamine oxidases A and B. XCT790 induces proteasomal degradation of ERR alpha and potentiates the degradation of the estrogen receptor ER alpha by fulvestrant . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-2-propenamide |
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| Gene, Accession, CAS # | CAS: 725247-18-7 |
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| Catalog # | LS-H122 |
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| Order / More Info | XCT790 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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