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| Product Name | CP 640,186 |
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| Description | Purity >95%. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA, a precursor for fatty acids. CP 640,186 is an isozyme-nonselective ACC inhibitor with IC50 values of 53 and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2, respectively. It has been shown to lower malonyl-CoA levels and to inhibit hepatic fatty acid and triglyceride synthesis both in vitro and in vivo . CP 640,186 can also stimulate muscle fatty acid oxidation (EC50 = 1.3 µM in rat epitrochlearis muscle strips) and lower whole body respiratory quotient in rats (ED50 = ~30 mg/kg). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(3R)-1'-(9-anthracenylcarbonyl)[1,4'-bipiperidin]-3-yl]-4-morpholinyl-methanone |
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| Gene, Accession, CAS # | CAS: 591778-68-6 |
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| Catalog # | LS-H7245 |
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| Order / More Info | CP 640,186 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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