| 产品详情 |
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| Product Name | NCT-503 |
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| Description | Purity >98%. NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM. It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in vitro and in mice bearing orthotopic xenograft tumors. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarbothioamide |
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| Gene, Accession, CAS # | CAS: 1916571-90-8 |
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| Catalog # | LS-H8941 |
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| Price | |
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| Order / More Info | NCT-503 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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