| 产品详情 |
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| Product Name | JNJ-42041935 |
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| Description | Purity >98% by HPLC. JNJ-42041935 is a HIF-PHD (Hypoxia-inducible factor- prolyl hydroxylase) inhibitor. JNJ-42041935 is a selective, 2-OG (2-oxoglutarate) competitive, and reversible inhibitor of PHD enzymes (pKis = 7.91, 7.29, and 7.65 for PHD1, 2, and 3, respectively). It is >100-fold selective for PHD compared to the related FIH (factor-inhibiting HIF) and a panel of various other enzymes. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic acid |
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| Gene, Accession, CAS # | CAS: 1193383-09-3 |
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| Catalog # | LS-H3783 |
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| Order / More Info | JNJ-42041935 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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