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| Product Name | Thiorphan |
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| Description | Purity >95%. Thiorphan is a potent inhibitor of neprilysin, a membrane metallo-endopeptidase that cleaves peptide hormones, such as enkephalins, glucagon, and bradykinin (Ki = 4-140 nM). It is much less effective against neprilysin-2 (IC50 = 22.1 µM), angiotensin-converting enzyme, and endothelin-converting enzyme-1. Thiorphan can be produced in vivo via the metabolism of the prodrug racecadotril . Neprilysin is overexpressed in many forms of cancer and may play a role in protecting against Alzheimer's disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(mercaptomethyl)-1-oxo-3-phenylpropyl]-glycine, DL-Thiorphan |
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| Gene, Accession, CAS # | CAS: 76721-89-6 |
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| Catalog # | LS-H10213 |
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| Price | |
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| Order / More Info | Thiorphan from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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