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| Product Name | Thrombin Receptor Agonist Peptide |
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| Description | Purity >95% by HPLC. Thrombin signaling of platelets is mediated by a G protein-coupled protease-activated receptor (PAR). The PAR is activated after thrombin binding and subsequent cleavage of the amino terminal end of the receptor. This new amino terminus acts as a tethered ligand and binds intramolecularly to the body of the PAR, resulting in a transmembrane signal. A synthetic thrombin receptor agonist peptide (TRP) of 6 residues (SFLLRN) corresponding to aa42-47 of the thrombin receptor was found to be as effective as thrombin for Ca2+ mobilization. TRAP can be used instead of thrombin to trigger platelet aggregation and clot retraction. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Thrombin Receptor Agonist Peptide, TRAP, Proteinase-activated receptor 1, PAR-1, Thrombin receptor, Coagulation factor II receptor, F2R, CF2R, PAR1, TR |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H5347 |
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| Order / More Info | Thrombin Receptor Agonist Peptide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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