| 产品详情 |
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| Antigenic Specificity | CD276 / B7-H3 |
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| Clone | MIH42 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:10 - 1:100), IHC, IHC-Fr (1:100), IHC-P (10 µg/ml) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD276 / B7-H3 Antibody (clone MIH42) IHC-plus™ LS-B2614. Detects CD276, a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. |
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| Immunogen | n/a |
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| Other Names | CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 molecule, Costimulatory molecule, B7H3, B7RP-2 |
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| Gene, Accession # | CD276, Gene ID: 80381 |
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| Catalog # | LS-B2614 |
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| Price | |
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| Order / More Info | CD276 / B7-H3 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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